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BAY 2965501

CAS No. 2732902-08-6

BAY 2965501( —— )

Catalog No. M36493 CAS No. 2732902-08-6

BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation, and it can be utilized in cancer research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BAY 2965501
  • Note
    Research use only, not for human use.
  • Brief Description
    BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor that induces pERK activation, and it can be utilized in cancer research.
  • Description
    BAY 2965501 is a potent and selective diacylglycerol kinase zeta (DGKζ) inhibitor. BAY 2965501 induces pERK activation. BAY 2965501 can be used for the research of cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    PERK
  • Recptor
    PERK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2732902-08-6
  • Formula Weight
    414.45
  • Molecular Formula
    C20H19FN4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : ≥ 100 mg/mL (241.28 mM)
  • SMILES
    N([C@@H](C(N)=O)C)(C=1SC(C(=O)C2=CC=C(OC)C=C2)=C(N)N1)C3=CC=C(F)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Schubert N, et al. Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGKζ inhibitor BAY2965501 in clinical trials. Cancer Research, 2023, 83(7_Supplement): 2116-2116.
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